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Ablynx's osteoporosis nanobody enters clinic
16 December 2009
Sukaina Virji

Ablynx of Belgium has began clinical testing of a fourth nanobody, ALX-0141, for the treatment of osteoporosis. ALX-0141 targets Receptor Activator of Nuclear Factor kappa B Ligand (RANKL), a key regulator of bone resorption.

Overproduction of RANKL is implicated in a variety of degenerative...



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