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Research & Development - Clinical Trials
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The privately owned French biotech firm Bioprojet says that its new compound for excessive daytime sleepiness (EDS), pitolisant, has shown good results in several European Phase II trials and has now begun Phase III development. The product, which ...
Pfizer is facing more disappointment with the development of some of its most advanced anticancers after Sutent (sunitinib) failed two more Phase III trials in advanced breast cancer - ending development for the drug in the disease - and figitumumab ...
Singapore has launched a new national cancer centre which it expects to play a key role in the advancement of novel therapies for malignancies prevalent in the Asia-Pacific region. The National University Cancer Institute, Singapore, was formally ...
The European Commission will provide €12 million in funding for two new research projects which will develop novel influenza treatments, including against both (A) H1N1 pandemic influenza and (A) H5N1 avian flu. Speaking at an EU influenza meeting ...
PTC Therapeutics and Genzyme 's ataluren, an experimental nonsense mutation suppressor, has failed in nonsense mutation Duchenne/Becker Muscular Dystrophy (nmDBMD), show top-line Phase IIb results. Around 10-15% of DBMD cases are due to nonsense ...
 
The therapeutic landscape in HCV treatment is at an inflection point – recent data from the first generation of protease inhibitors promise the dawn of a new standard of care. But do not expect to ...
Several promising new multiple sclerosis drugs are poised to make their debut on the market within the next few years. What effect will they have on the treatment paradigm for this debilitating ...
Recent developments in the field of active cancer immunotherapy foreshadow that the "next big thing" in cancer drugs may be on the way. Yet appropriately designed clinical trials testing combination ...
 
After years of anti-obesity disappointments, Orexigen's Contrave, Vivus's Qnexa and Arena's lorcaserin stand on the verge of being filed with the US FDA. Professor Michael Cowley, inventor of ...
Since becoming CEO of Evotec Dr Werner Lanthaler has overseen a string of deals as well as upheavals at the company. He spoke to Scrip's Simon Varcoe about how the German firm has been transformed ...
While many venture capital (VC) firms have dropped beneath the radar during the current credit squeeze, Abingworth is one of the few that is not just visible but appears to be operating on a business ...
 
GlaxoSmithKline will enter unknown regulatory waters when it eventually comes to seek approval of its paediatric malaria vaccine, RTS,S, the most advanced in development for this disease. The ...
The total investments secured by private companies slumped once more in June, disappointing onlookers hoping that May's healthy performance was a sign of recovery in the market, a Scrip analysis has ...
Cancer treatment is undergoing a revolution, driven by ageing populations, advanced technologies and an increasingly informed society. Health economics considerations and top-up payments are gaining ...
 
For the last half-century, despite its many limitations warfarin has been the mainstay of treatment for patients with venous and arterial thromboembolic disease. During the past decade, a number of ...
mTOR was determined to be a promising anticancer target and several drug inhibitors of mTOR are currently in clinical development. Rapamycin (RAP) was the first mTOR inhibitor discovered. However, ...
Background: Therapy for multiple sclerosis (MS) has changed dramatically over the past decade, yielding significant progress in the treatment of relapsing/remitting and secondary progressive MS. ...
 
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